Weinan is dedicated to developing large-scale, chronic, bidirectional electrophysiology platforms based on ultraflexible nanoelectronic thread (NET) probes. His work bridges spatial and temporal scales in neural recording and stimulation, from millisecond-level neural dynamics to months- and years-long chronic studies, and from single-cell resolution to distributed brain-wide circuits. He approaches this goal through two complementary directions: increasing electrode site density within a limited implantation footprint using electron-beam lithography-patterned high-density interconnects, and developing an automated platform for simultaneous, configurable, multi-shank NET implantation across the brain. In collaboration with ASIC designers, he works toward integrated neural interface systems that are scalable, practical, and accessible for chronic in vivo studies. By expanding the input/output bandwidth between NET-based probes and the brain while preserving long-term tissue integration, his work aims to enable stable tracking and modulation of neuronal activity across distributed brain regions over extended timescales.